The Segal Lab has published a new (July 16, 2018) paper in the Journal of Neuroinflammation detailing evidence of a previously undiscovered mechanism in which cytokines IFNγ and CXCL2 interact to regulate central nervous system lesion location in an experimental allergic encephalomyelitis (EAE) mouse model. You can read the full abstract via PubMed at this link.
Footer
Contact Information
109 Zina Pitcher Place
4014-B BSRB
Ann Arbor, MI 48109
Phone: (734) 615-5635
Fax: (734) 615-7300
Most Recent Manuscripts
- An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE.
- A randomized, subject and rater-blinded, placebo-controlled trial of dimethyl fumarate for obstructive sleep apnea.
- Modulation of the Innate Immune System: A Future Approach to the Treatment of Neurological Disease.
- Americas Committee for Treatment and Research in Multiple Sclerosis Forum 2017: Environmental factors, genetics, and epigenetics in MS susceptibility and clinical course.
- GM-CSF Promotes Chronic Disability in Experimental Autoimmune Encephalomyelitis by Altering the Composition of Central Nervous System-Infiltrating Cells, but Is Dispensable for Disease Induction.